乳房保留手術後女性為再發性乳癌高危險群, 乳房磁振造影( MRI) 檢查益於曾接受乳房保留手術的女性

乳房磁振造影檢查益於曾接受乳房保留手術的女性

3月17日在放射醫學雜誌網站上發表了一項研究，針對患有早期乳腺癌並接受乳房保留手術(BCT)的女性患者，可藉由乳房磁振造影檢查檢測癌症的復發。

研究人員針對這類婦女進行回顧性研究，挑選607位婦女，共接受過932次的乳房磁振造影檢查，BCT手術結束後，以乳房攝影及乳房超音波追蹤檢查皆為正常。

研究人員集中在癌症的檢測率和檢測癌症的特點，以及陽性預測值，靈敏度和特異性。 乳房磁振造影檢查產生了18.1％的1,000整體癌症的檢出率，確定11個癌症中，其中8個為浸潤性癌症和其中3個原位癌。敏感性為91.7 ％和特異性分別為82.2 ％，而陽性預測值和召回的9.4 ％和43.5％分別活檢。

該研究發現，乳房磁振造影檢查檢測癌症較易於為年齡小於50歲，及接受首次乳房保留手術(BCT)已超過24個月的患者有幫助可發現早期乳癌。

Comment: 但健保考慮費用應該不會同意乳房磁振造影檢查

Single-Screening MRI Beneficial for Women With Breast Conservation Therapy History

A study published online March 17 in the journal Radiology suggests that certain women with a history of breast conservation therapy (BCT), following treatment of early-stage breast cancer, may benefit from MRI screening to detect secondary cancers.

Researchers conducted a retrospective study of 607 women who underwent 932 MRI screening exams, following previous negative mammography and ultrasonographic results. The researchers focused on cancer detection rate and the characteristics of detected cancers, as well positive predictive value, sensitivity, and specificity. MRI screening yielded an overall cancer detection rate of 18.1 per 1,000, identifying 11 cancers in total, eight of which were invasive ductal carcinomas and three of which were ductal carcinomas in situ. Sensitivity of the screenings was 91.7 percent and specificity was 82.2 percent, with positive predictive values for recall and biopsy of 9.4 percent and 43.5 percent, respectively. The study found that those who developed MRI-detected cancers were more likely to be younger than 50 and had undergone initial surgery more than 24 months before screening.

  A study published online Mar. 17 by Radiology.